Depressants, Barbiturates, Sedatives, and Tranquilizers

I.               What are Depressants?

A.    Depressants are drugs that depress people. 

B.    They are drugs that slow down functions in the body.

C.    Usually these are taken to calm a person down, or help that person sleep.

II.             What are some examples of depressants?

A.    Some examples would be tranquilizers, barbiturates, inhalants and chloral hydrate.

B.    Brand / Generic Names

1.     Secobarbital, Phetobarbital, Amobarbital, Amosecobarbital, Phenobarbital, Chloral Hydrate, Glutethimide, Methyprylon, Methaqualone, Diphenhydramine Hydrochloride, Chlordiazepoxide, Diazepam, Diphenhylhydantoin Sodium, Flurazepam, Alprazolam, Phenelzine Sulfate, Amitriptyline Hydrochloride, Desipramine, Doxepin Hydrochloride, Lithium Carbonate, Lithium Citrate, Droperidol, Chlorpromazine, Alcohol

C.    Barbiturates

1.     What are they?  - Barbiturates are depressants that affect the central nervous system (CNS).

2.     Depressants act as downers, and can slow the body and mind down.

3.     There are over 2,000 known barbiturates.

4.     Street Names: Barbs, downers, sleepers, stumblers, blues, yellow jackets, purple hearts, red dolls, rainbows,  tootsies

5.     How is it taken?  - Taken orally (pills of various colors)

6.     The Scoop on Barbiturates

a.     Barbiturates are some of the of the most addictive drugs. 

b.     They are often a substitute for alcohol (as similar effects are produced.)

c.     People use Barbiturates to get a sense of euphoria and relaxation.

d.     However, it is illegal to take barbiturates with out a doctor's prescription and supervision

7.     Short Term Effects of Barbiturates: (last for 15 hours after ingestion)

a.     Relief of tension and anxiety

b.     Sleepiness

c.     Feeling of drunkenness / intoxication

d.     Slurred speech

e.     Inability to control simple bodily functions (walking, balance, etc...)

f.      Memory impairment

g.     Emotional instability

8.     Long Term Effects of Barbiturates:

a.     Chronic tiredness

b.     General uncoordination

c.     Vision problems

d.     Dizziness

e.     Slowed reflexes and response

f.      Sexual dysfunction

g.     Menstrual irregularities

h.     Breathing disorders

9.     Tolerance:

a.     Develops very rapidly

b.     Ten times the original dosage may be required to produce the same high

10.   Withdrawal symptoms:

a.     Hallucinations

b.     Eating disorders

c.     Disorientation

d.     Vomiting

e.     Sleep disorders

11.   Barbiturates and other depressants:

a.     The combination of barbiturates and other drugs is very dangerous (especially when combined with other CNS Depressants like Demerol, heroin, morphine, and codeine).

b.     Barbiturates produce many of the same effects as alcohol, and the combination of the two is often lethal.

c.     There is a hidden danger with barbiturate use, especially if you suffer from allergies.

d.     Antihistamines (found in most allergy, cold, and sinus medicine) are another type of CNS Depressants, and when taken with barbiturates, can cause respiratory arrest.

D.    Tranquilizers

1.     Tranquilizers are depressant drugs that can be used to treat anxiety or insomnia.

2.     Sedatives are used as a sleep aid or relaxer and anti anxiety tranquilizers are used to gain a sense of well-being or to reduce feelings of panic or tension.

3.     Like alcohol, tranquilizers work to depress brain functions which can cause impaired thinking and memory loss, emotional instability, altered perceptions and slurred speech.

4.     Common Names - BuSpar, Equanil, Miltown, Librium, Valium, Serax Clonpin, Calmane, Halcion

5.     Short-term Effects

a.     Relief of anxiety or tension

b.     Sense of relaxation

c.     Sense of well-being

d.     Impairment of memory

e.     Drowsiness

f.      Confusion

g.     Stupor

6.     Long-term Effects

a.     Lethargy and over sedation

b.     Decreased motivation

c.     Irritability

d.     Vivid or disturbing dreams

e.     Nausea

f.      Headache

g.     Skin rash

h.     Impaired sexual functioning

i.       Menstrual irregularities

j.       Tremors

k.     Loss of appetite or increased appetite

7.     Under the class of sedatives, GHB and Rohypnol are popularly known as date rape drugs.

a.     In many instances, victims are drugged when their drinks are spiked with GHB or Rohypnol. 

b.     They may wake up the next day not knowing how they got where they are or what happened the night before.

E.     Diazepam ( T-Quil, Valrelease, Valium )

1.     Diazepam is an antianxiety agent ( benzodiazepines. )

2.     Used primarily for short-term relief of mild to moderate anxiety.

3.     It may also be used to treat symptoms of acute alcohol withdrawals, to help control epilepsy and to relieve muscle spasms.

III.            What are they usually called?

A.    Some slang terms would be redbirds, peanuts, V's, yellows and blue devils.

1.     Reds, Red Devils, RD's, Fender Benders, Yellows, Yellow Jackets, Blues, Blue Heavens, Rainbows, Christmas Trees, Pink Ladies, Mickey Finn, Knockout Drops, Ludes, Barbs, Downers, Busters, Butisol, Courage Pill, Florinal, G.B.'s, Goof Balls, Green Dragons, King Kong Pills, Lotusate, Peanuts

 

IV.           How do they affect the body?

A.    Possible Effects of Depressants

1.     Central nervous system depressants slow down the operation of the brain.

2.     They first affect those areas of the brain that control a person’s conscious, voluntary actions.

3.     As dosage increases, depressants begin to affect the parts of the brain controlling the body’s automatic, unconscious processes, such as heartbeat and respiration.

4.     Alcohol is the most familiar, and most widely abused depressant. With some exceptions, all depressants affect people in much the same way as does alcohol.

B.    Most depressant users ingest these drugs orally.

C.    However, a few abusers will inject their drugs intravenously.

D.    The injection paraphernalia used by barbiturate abusers are similar to those used by heroin addicts, although a wider gauge hypodermic needle is used, because the barbiturate solution is thicker than the heroin solution.

E.     The injection sites on the skin of a barbiturate abuser exhibit large swellings, and may develop ulceration’s resembling cigarette burns.

F.     The affects of depressants are once again compared to those of alcohol.

1.     Reduced social inhibitions impaired ability to divide attention slow reflexes impaired judgment and concentration impaired vision and coordination slurred, mumbled or incoherent speech a wide variety of emotional effects, such as euphoria, depression, suicidal tendencies, laughing or crying for no apparent reason, etc.

G.    Depressants vary in the amount of time it takes the user to feel the effects and also the amount of time the effects are felt.

H.    Some depressants act very quickly, and begin to affect their user within seconds.

I.      Others act more slowly, sometimes taking one-half hour or more to begin to exert an influence.

J.      The quick-acting depressants also tend to be relatively short acting: in some cases their effects wear off in a matter of minutes.

K.    The slow-acting depressants, on the other hand, tend to produce longer-acting effects.

L.     Overdoses of depressants produce effects that are the same as alcohol overdoses. The person becomes extremely drowsy and pass out.

1.     Their heartbeat slows and respiration will become shallow.

2.     Their skin may feel cold and clammy, and death may result from respiratory failure.

M.   One way that they affect the body is that they cause sleep disorders. 

N.    If an overdose is taken, it may cause death. 

O.    If you try to get off, you could die.

 

 

 

References

 

PSYweb - Valium (Diazepam). http://www.psyweb.com/Drughtm/valium.html. 2000. psyweb.

 

 

Neuropharmacology of Sedatives and Anxiolytics. http://www.biopsychiatry.com/anxsed.html. 2001. biopsychiatry.com.

 

Information on Barbiturates . http://www.hfni.gsehd.gwu.edu/~sapc/barbiturates.htm. 2001. gwu.edu.

 

 

Information on Tranquilizers and Sedatives. http://www.hfni.gsehd.gwu.edu/~sapc/sedatives.html. 2001. gwu.edu.  

 

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